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KMID : 0366220070420040409
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Korean Journal of Hematology
2007 Volume.42 No. 4 p.409 ~ p.413
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A Case of Massive Intravascular Hemolysis Associated with Clostiridium perfringens Sepsis
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Park Kyung-Sun
Kang So-Young
Lee Woo-In
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Abstract
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Clostridium perfringens is an anaerobic, gram-positive rod that inhabits the soil and the intestinal tracts of many animals, including humans. C. perfringens is a major cause of food poisoning, traumatic or nontraumatic myonecrosis, clostridial cellulitis, gangrenous cholecystitis, sepsis or bacteremia, and intravascular hemolysis. Massive intravascular hemolysis is a rare complication of C. perfringens septicemia and has a high mortality rate with an extremely rapid progression. Therefore, aggressive treatment is required as soon as the diagnosis is made. In this study, we report a case of massive intravascular hemolysis due to C. perfringens septicemia in a 34-year-old man with liver cirrhosis. (Korean J Hematol 2007; 42:409-413.)
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KEYWORD
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Clostiridium perfringens, Massive intravascular hemolysis, Sepsis
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